Identification and characterization of an efficient acyl-CoA: diacylglycerol acyltransferase 1 (DGAT1) gene from the microalga Chlorella ellipsoidea
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منابع مشابه
Influence of the Bovine Acyl-Coa: Diacylglycerol Acyltransferase1 (DGAT1) K232A on Milk Production and Somatic Cell Score Holstein Cows
This experiment was aimed to study the association between the DGAT1 K232A polymorphism and milk production traits and somatic cell score (SCS) in Iranian Holstein dairy cows. The records of 408 animals from five dairy herds were randomly identified and then genomic DNA was extracted from blood using the modified-salting method described by Miller. RFLP-PCR was performed to obtain all the polym...
متن کاملInfluence of the Bovine Acyl-Coa: Diacylglycerol Acyltransferase1 (DGAT1) K232A on Milk Production and Somatic Cell Score Holstein Cows
This experiment was aimed to study the association between the DGAT1 K232A polymorphism and milk production traits and somatic cell score (SCS) in Iranian Holstein dairy cows. The records of 408 animals from five dairy herds were randomly identified and then genomic DNA was extracted from blood using the modified-salting method described by Miller. RFLP-PCR was performed to obtain all the polym...
متن کاملDiacylglycerol Acyltransferase-1 (DGAT1) Inhibition Perturbs Postprandial Gut Hormone Release
Diacylglycerol acyltransferase-1 (DGAT1) is a potential therapeutic target for treatment of obesity and related metabolic diseases. However, the degree of DGAT1 inhibition required for metabolic benefits is unclear. Here we show that partial DGAT1 deficiency in mice suppressed postprandial triglyceridemia, led to elevations in glucagon-like peptide-1 (GLP-1) and peptide YY (PYY) only following ...
متن کاملIncreased insulin and leptin sensitivity in mice lacking acyl CoA : diacylglycerol acyltransferase 1 Hubert
Because obesity results from an imbalance between energy input and output, with most of the excess calories stored as triglycerides (or triacylglycerols), inhibition of triglyceride synthesis may prevent or reverse obesity (1). One of the key enzymes in triglyceride synthesis is acyl coenzyme A:diacylglycerol acyltransferase (acyl CoA:diacylglycerol acyltransferase, or DGAT), which catalyzes th...
متن کاملچند شکلی در اگزون 17 ژن DGAT1 و ارتباط آن با صفات تولید شیر در بزهای نژاد مهابادی با روش PCR-SSCP
Diacylglycerol transferase is a microsome enzyme that plays an important role in glycerol lipid metabolism. The acyl CoA-diacylglycerol- acyltransferase 1 (DGAT1) is considered to be the key enzyme in controlling the synthesis of triglycerides in adipocytes. This enzyme catalyzes the final step of triglyceride synthesis (transform triacylglycerol (DAG) into triacylglycerol (TAG). The present st...
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ژورنال
عنوان ژورنال: BMC Plant Biology
سال: 2017
ISSN: 1471-2229
DOI: 10.1186/s12870-017-0995-5